http://kulan.cz/index.php?title=Rifampicin&action=history Historie editací této stránky cs MediaWiki 1.15.1 Mon, 13 Apr 2026 05:36:37 GMT http://kulan.cz/index.php?title=Rifampicin&diff=3367&oldid=prev <p>Stránka vyprázdněna</p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 24. 1. 2011, 19:07</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 1:</td> <td colspan="2" class="diff-lineno">Řádka 1:</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Makrocyklické ansamycinové ATB </del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">baktericidní na rostoucí bakterie </del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">'''účinek:''' inhibice syntézy bakt. RNA, inhibice ''DNA dependentní RNA polymerázy'' </del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">širokospektrý - chlamidie, legionely, mykobakterie, ''s. aureus'' (včetně MRSA), ''s. epidermidis'', ''n. meningitidis'', ''h. influenzae'' </del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">'''užití''' - zejména u '''tuberkulózy''', dále endokarditidy, osteomyelitidy, legionely, lepra, rezistentní stafylokoky, většinou v kombinaci s jiným ATB</del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">'''Farmakokinetika''' - distribuce i skrz BBB, metabolizace játry, vylučování žlučí </del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">'''podávání''' - p.o. po 8 hodinách </del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">'''NÚ''' - hepatotoxicita, potencuje CYP - řada interakcí </del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">barví moč, sliny, slzy a pot oranžově </del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">rezistence vzniká velmi rychle (už během léčby) - vhodné kombinovat s dalšími ATB </del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">[[category:Farmakologie]]</del></div></td><td colspan="2">&nbsp;</td></tr> <!-- diff generator: internal 2026-04-13 05:36:37 --> </table> Mon, 24 Jan 2011 19:07:09 GMT Kulan http://kulan.cz/Diskuse:Rifampicin http://kulan.cz/index.php?title=Rifampicin&diff=3162&oldid=prev <p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 22. 1. 2011, 05:13</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 19:</td> <td colspan="2" class="diff-lineno">Řádka 19:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>rezistence vzniká velmi rychle (už během léčby) - vhodné kombinovat s dalšími ATB &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>rezistence vzniká velmi rychle (už během léčby) - vhodné kombinovat s dalšími ATB &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[category:<del class="diffchange diffchange-inline">Léčiva</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>&#160;</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[category:<ins class="diffchange diffchange-inline">Farmakologie</ins>]]</div></td></tr> <!-- diff generator: internal 2026-04-13 05:36:37 --> </table> Sat, 22 Jan 2011 05:13:30 GMT Kulan http://kulan.cz/Diskuse:Rifampicin http://kulan.cz/index.php?title=Rifampicin&diff=894&oldid=prev <p>Založena nová stránka: Makrocyklické ansamycinové ATB baktericidní na rostoucí bakterie &#39;&#39;&#39;účinek:&#39;&#39;&#39; inhibice syntézy bakt. RNA, inhibice &#39;&#39;DNA dependentní RNA polymerázy&#39;&#39; širok…</p> <p><b>Nová stránka</b></p><div>Makrocyklické ansamycinové ATB <br /> <br /> baktericidní na rostoucí bakterie <br /> <br /> '''účinek:''' inhibice syntézy bakt. RNA, inhibice ''DNA dependentní RNA polymerázy'' <br /> <br /> širokospektrý - chlamidie, legionely, mykobakterie, ''s. aureus'' (včetně MRSA), ''s. epidermidis'', ''n. meningitidis'', ''h. influenzae'' <br /> <br /> '''užití''' - zejména u '''tuberkulózy''', dále endokarditidy, osteomyelitidy, legionely, lepra, rezistentní stafylokoky, většinou v kombinaci s jiným ATB<br /> <br /> '''Farmakokinetika''' - distribuce i skrz BBB, metabolizace játry, vylučování žlučí <br /> <br /> '''podávání''' - p.o. po 8 hodinách <br /> <br /> '''NÚ''' - hepatotoxicita, potencuje CYP - řada interakcí <br /> <br /> barví moč, sliny, slzy a pot oranžově <br /> <br /> rezistence vzniká velmi rychle (už během léčby) - vhodné kombinovat s dalšími ATB <br /> <br /> [[category:Léčiva]]</div> Mon, 21 Dec 2009 09:17:54 GMT Kulan http://kulan.cz/Diskuse:Rifampicin