http://kulan.cz/index.php?action=history&feed=atom&title=Podp%C5%AFrn%C3%A1_l%C3%A9%C4%8Dba_v_onkologii 2026-04-13T05:50:23Z Historie editací této stránky MediaWiki 1.15.1 http://kulan.cz/index.php?title=Podp%C5%AFrn%C3%A1_l%C3%A9%C4%8Dba_v_onkologii&diff=8759&oldid=prev 2018-06-03T21:42:54Z

<p>Stránka <a href="/Podp%C5%AFrn%C3%A1_l%C3%A9%C4%8Dba" class="mw-redirect" title="Podpůrná léčba">Podpůrná léčba</a> přemístěna na stránku <a href="/Podp%C5%AFrn%C3%A1_l%C3%A9%C4%8Dba_v_onkologii" title="Podpůrná léčba v onkologii">Podpůrná léčba v onkologii</a></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 3. 6. 2018, 21:42</td> </tr> <!-- diff generator: internal 2026-04-13 05:50:23 --> </table>

Kulan http://kulan.cz/index.php?title=Podp%C5%AFrn%C3%A1_l%C3%A9%C4%8Dba_v_onkologii&diff=8758&oldid=prev 2018-06-03T21:42:39Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 3. 6. 2018, 21:42</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 184:</td> <td colspan="2" class="diff-lineno">Řádka 184:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Interna]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Interna]]</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[category:<del class="diffchange diffchange-inline">Nádory</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[category:<ins class="diffchange diffchange-inline">Onkologie</ins>]]</div></td></tr> <!-- diff generator: internal 2026-04-13 05:50:23 --> </table>

Kulan http://kulan.cz/index.php?title=Podp%C5%AFrn%C3%A1_l%C3%A9%C4%8Dba_v_onkologii&diff=8266&oldid=prev 2018-05-04T20:31:24Z

<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 4. 5. 2018, 20:31</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 1:</td> <td colspan="2" class="diff-lineno">Řádka 1:</td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>U nádorových nemocí se vyskytují nejrůznější obtíže a komplikace, způsobeny progredujícím nádorovým onemocněním nebo jsou v přímé souvislosti s protinádorovou léčbou. Kvalita života nemocných se dá zlepšit adekvátní léčbou. &nbsp;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>U nádorových nemocí se vyskytují nejrůznější obtíže a komplikace, způsobeny progredujícím nádorovým onemocněním nebo jsou v přímé souvislosti s protinádorovou léčbou. Kvalita života nemocných se dá zlepšit adekvátní <ins class="diffchange diffchange-inline">podpůrnou </ins>léčbou. &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2" class="diff-lineno">Řádka 177:</td> <td colspan="2" class="diff-lineno">Řádka 177:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>+ pomocné léky (antikonvulziva, centrální myorelaxancia, neuroleptika, antidepresiva, &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>+ pomocné léky (antikonvulziva, centrální myorelaxancia, neuroleptika, antidepresiva, &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">== Kachexie == </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">'''glukokortikoidy''' - u části pacietnů mají až euforizující efekt a zvyšují apetit a vedou k přibývání na váze </ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">(ale u jiných pacientů naopak vede k depresím, proteolýze)</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Interna]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Interna]]</div></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2">&nbsp;</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Nádory]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Nádory]]</div></td></tr> <!-- diff generator: internal 2026-04-13 05:50:23 --> </table>

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<p></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 4. 5. 2018, 15:06</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 180:</td> <td colspan="2" class="diff-lineno">Řádka 180:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>&#160;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">[[category:Interna]]</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Nádory]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[category:Nádory]]</div></td></tr> <!-- diff generator: internal 2026-04-13 05:50:23 --> </table>

Kulan http://kulan.cz/index.php?title=Podp%C5%AFrn%C3%A1_l%C3%A9%C4%8Dba_v_onkologii&diff=1096&oldid=prev 2010-02-07T20:56:22Z

<p><span class="autocomment">Bolest</span></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 7. 2. 2010, 20:56</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 167:</td> <td colspan="2" class="diff-lineno">Řádka 167:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Bolest ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Bolest ==</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">jeden z nejčastějších symptomů, které doprovázejí nádorová onemocnění </ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">u čtvrtiny až poloviny nemocných je bolest prvním příznakem nádorového onemocnění </ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">v asi 70% případů je způsobena šířením primárního nádoru nebo metastáz do měkkých tkání, nervových struktur nebo kosti</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">-&gt; NSA -&gt; slabý opiár -&gt; silný opiát -&gt; neurochirurgické a anesteziologické formy léčby bolesti </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">+ pomocné léky (antikonvulziva, centrální myorelaxancia, neuroleptika, antidepresiva, </ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <!-- diff generator: internal 2026-04-13 05:50:23 --> </table>

Kulan http://kulan.cz/index.php?title=Podp%C5%AFrn%C3%A1_l%C3%A9%C4%8Dba_v_onkologii&diff=1095&oldid=prev 2010-02-07T20:49:44Z

<p><span class="autocomment">Neurotoxicita</span></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 7. 2. 2010, 20:49</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 154:</td> <td colspan="2" class="diff-lineno">Řádka 154:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>prevencí je dostatečná hydratace a podávání uroprotektiva mesny.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>prevencí je dostatečná hydratace a podávání uroprotektiva mesny.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>== Neurotoxicita == &nbsp;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>== Neurotoxicita ==</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">nejsou život ohrožující, ale mohou výrazně zhoršit kvalitu života </ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">encefalopatie (somnolence, sopor, kóma, amence, delírium) </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">myelopatie nejčastěji při intrathékální aplikaci cytostatik (až parézy/plegie, poruchy čití a funkce sfinkterů) </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">ortotoxicita + tinitus (cisplatina) </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">parestézie, nejdříve prstů</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Bolest ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Bolest ==</div></td></tr> <!-- diff generator: internal 2026-04-13 05:50:23 --> </table>

Kulan http://kulan.cz/index.php?title=Podp%C5%AFrn%C3%A1_l%C3%A9%C4%8Dba_v_onkologii&diff=1093&oldid=prev 2010-02-07T20:32:21Z

<p><span class="autocomment">Urotoxicita</span></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 7. 2. 2010, 20:32</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 143:</td> <td colspan="2" class="diff-lineno">Řádka 143:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>klinicky pokles glomerulární filtrace a hypomagnezinémie</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>klinicky pokles glomerulární filtrace a hypomagnezinémie</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>== Urotoxicita == &nbsp;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>== Urotoxicita ==</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins class="diffchange diffchange-inline">u některých cytostatik hemoragická cystitida (stáza moči s toxickými metabolity cytostatik) </ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">především v souvislosti s léčbou cyklofosfamidem </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">hemoragie může a nemusí být makroskopická </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">výjimečně i příčinou úmrtí, dojde-li k dedvinnému selhávání v důsledku obstrukce močových cest koaguly </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">prevencí je dostatečná hydratace a podávání uroprotektiva mesny.</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Neurotoxicita == &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Neurotoxicita == &nbsp;</div></td></tr> <!-- diff generator: internal 2026-04-13 05:50:23 --> </table>

Kulan http://kulan.cz/index.php?title=Podp%C5%AFrn%C3%A1_l%C3%A9%C4%8Dba_v_onkologii&diff=1092&oldid=prev 2010-02-07T20:23:06Z

<p><span class="autocomment">Nefrotoxicita</span></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 7. 2. 2010, 20:23</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 133:</td> <td colspan="2" class="diff-lineno">Řádka 133:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>Mezi nejvíce nefrotoxické léky patří cisplatina (akutní reverzibilní i chronické a ireverzibilní poškození)</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>Mezi nejvíce nefrotoxické léky patří <ins class="diffchange diffchange-inline">'''</ins>cisplatina<ins class="diffchange diffchange-inline">''' </ins>(akutní reverzibilní i chronické a ireverzibilní poškození)</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>prevence v intenzivní hydrataci a forsírovaná diuréza</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>prevence v intenzivní hydrataci a forsírovaná diuréza</div></td></tr> <!-- diff generator: internal 2026-04-13 05:50:23 --> </table>

Kulan http://kulan.cz/index.php?title=Podp%C5%AFrn%C3%A1_l%C3%A9%C4%8Dba_v_onkologii&diff=1091&oldid=prev 2010-02-07T20:22:50Z

<p><span class="autocomment">Nefrotoxicita</span></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 7. 2. 2010, 20:22</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 126:</td> <td colspan="2" class="diff-lineno">Řádka 126:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>nejčastějšími projevy jsou intersticiální akutní pneumonitida s možným přechodem do plicní fibrózy, akutní hypersenzitivní reakce a nekardiální plicní edém.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>nejčastějšími projevy jsou intersticiální akutní pneumonitida s možným přechodem do plicní fibrózy, akutní hypersenzitivní reakce a nekardiální plicní edém.</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>== Nefrotoxicita == &nbsp;</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>== Nefrotoxicita ==</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">možná infiltrace glomerulů metastázami, ischémie trombózou a. renalis, nebo paraneoplastická glomerulonefritida </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">častější poškození ledvin v souvislosti s léčbou, buďto přímou toxicitou cytostatik nebo v důsledku rychlého rozpadu tumoru (syndrom akutní lýzy tumoru) </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">Mezi nejvíce nefrotoxické léky patří cisplatina (akutní reverzibilní i chronické a ireverzibilní poškození)</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">prevence v intenzivní hydrataci a forsírovaná diuréza</ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">HUS u 2-10% kéčených mitomycinem C </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">klinicky pokles glomerulární filtrace a hypomagnezinémie</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Urotoxicita == &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Urotoxicita == &nbsp;</div></td></tr> <!-- diff generator: internal 2026-04-13 05:50:23 --> </table>

Kulan http://kulan.cz/index.php?title=Podp%C5%AFrn%C3%A1_l%C3%A9%C4%8Dba_v_onkologii&diff=1090&oldid=prev 2010-02-07T20:06:52Z

<p><span class="autocomment">Pneumotoxicita</span></p> <table style="background-color: white; color:black;"> <col class='diff-marker' /> <col class='diff-content' /> <col class='diff-marker' /> <col class='diff-content' /> <tr valign='top'> <td colspan='2' style="background-color: white; color:black;">← Starší verze</td> <td colspan='2' style="background-color: white; color:black;">Verze z 7. 2. 2010, 20:06</td> </tr> <tr><td colspan="2" class="diff-lineno">Řádka 119:</td> <td colspan="2" class="diff-lineno">Řádka 119:</td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* nerovnováha mezi syntézou a degradací kolagenu &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* nerovnováha mezi syntézou a degradací kolagenu &nbsp;</div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* inaktivací plicního antiproteázového systému.</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>* inaktivací plicního antiproteázového systému.</div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">* některá cytostatika přímo poškozují cévní stěnu </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">(bleomycin, busulfan) </ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2">&nbsp;</td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">nejčastějšími projevy jsou intersticiální akutní pneumonitida s možným přechodem do plicní fibrózy, akutní hypersenzitivní reakce a nekardiální plicní edém.</ins></div></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr> <tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Nefrotoxicita == &nbsp;</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Nefrotoxicita == &nbsp;</div></td></tr> <!-- diff generator: internal 2026-04-13 05:50:23 --> </table>

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